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10 Best Supplements for Muscle Gain and Weight Loss

last updated: Apr 22, 2021

Achieving weight loss muscle gain at the same time is hard work. As well as training heavy and eating smart, you have to get your supplementation plan on point. Yet, finding the best supplements for weight loss and muscle gain is tricky. In this article, we review the best supplements for fat loss and muscle gain in the market to build muscle while burning fat.

In a Hurry? The test winner after 31 hrs of research

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Labrada Nutrition Lean Body Protein Shake
94/100 our score
Materials
98
Ease of Use
97
Features
90
Side Effects
90
Product Purity
95
Labrada Nutrition Lean Body Protein Shake
Why is it better?

40 grams of protein

Zero sugar

22 vitamins and minerals

Our #1 rated proteinDon't miss this...
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Our #1 rated protein
Researched Sources
41
Researched Sources
Reviews Considered
12k
Reviews Considered
Hours Researching
31
Hours Researching
Products Evaluated
14
Products Evaluated
Sorting Options
Materials Ease of Use Features Side Effects Product Purity By Default
Rank
PictureProduct
Name
Rating
Shops
#1
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
94
Materials
98 %
Ease of Use
97 %
Features
90 %
Side Effects
90 %
Product Purity
95 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$38.49
#2
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
92.6
Materials
95 %
Ease of Use
95 %
Features
89 %
Side Effects
90 %
Product Purity
94 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$39.97
#3
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
90.4
Materials
90 %
Ease of Use
95 %
Features
87 %
Side Effects
90 %
Product Purity
90 %
Price Comparison Last Updated (25.12.24)
Amazon Link
#4
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
88.8
Materials
90 %
Ease of Use
90 %
Features
87 %
Side Effects
90 %
Product Purity
87 %
Price Comparison Last Updated (25.12.24)
Amazon Link
#5
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
87.2
Materials
85 %
Ease of Use
90 %
Features
86 %
Side Effects
90 %
Product Purity
85 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$49.99
#6
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
86.2
Materials
85 %
Ease of Use
85 %
Features
86 %
Side Effects
90 %
Product Purity
85 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$32.99
#7
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
85.6
Materials
85 %
Ease of Use
84 %
Features
85 %
Side Effects
90 %
Product Purity
84 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$21.99
#8
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.8
Materials
80 %
Ease of Use
82 %
Features
85 %
Side Effects
90 %
Product Purity
82 %
Price Comparison Last Updated (25.12.24)
Amazon Link
#9
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.4
Materials
80 %
Ease of Use
82 %
Features
85 %
Side Effects
90 %
Product Purity
80 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$64.99
#10
The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.2
Materials
80 %
Ease of Use
81 %
Features
85 %
Side Effects
90 %
Product Purity
80 %
Price Comparison Last Updated (25.12.24)
Amazon Link
$49.99

10 Best Supplements for Muscle Gain and Weight Loss

1. Labrada Nutrition Lean Body Protein Shake

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
94
image of Labrada Nutrition Lean Body Protein Shake
Amazon Link
Materials
98
Ease of Use
97
Features
90
Side Effects
90
Product Purity
95
best offer for today
Amazon Link
$38.49
Pros:

40 grams of protein

Zero sugar

22 vitamins and minerals

Cons:

Uses sucralose

The Labrada Nutrition Supplement will help you attain the lean body you are trying for. This product contains fast-release proteins and slow-release proteins which will help with your amino acids by enhancing muscle growth and strength. It also has an award-winning taste.
Lean Body has won 5 times from the American Culinary Institute’s Gold Medal Award for Taste. This supplement for weight loss and muscle gain has everything you need. You also do not have to worry about putting junk in your body. It does not have artificial colors preservatives, aspartame, or trans fats making it the best fat burner and muscle builder combo on our list.

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Labrada Nutrition Lean Body Protein Shake provides a great combination of fat loss and weight gain. It provides a massive 40 grams of quality whey protein to build lean muscle mass. There is zero sugar to go with that protein, so you don’t have to worry about gaining fat with your muscle gains. This RTD product tastes like a frothy milkshake and comes in a range of great flavors.

Labrada’s Lean Body Protein Shake is fortified with 22 vitamins and minerals, providing you with a complete meal in a shake. With increasing protein levels being a great way to shed body fat, this product is the ideal muscle gain / fat loss solution. There is zero gluten and lactose in this product.

2. Legion Forge

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
92.6
image of Legion Forge supplement
Amazon Link
Materials
95
Ease of Use
95
Features
89
Side Effects
90
Product Purity
94
best offer for today
Amazon Link
$39.97
Pros:

Designed for fasted state training

Preserves muscle mass

Boosts brain functioning

Cons:

No caffeine

The Legion Forge supplement is designed to get rid of belly fat using the fat burner yohimbine. It works for men or women to help you get rid of that stubborn fat, even in your legs and butt. Your love handles will disappear and you will get that flat stomach. It contains the HMB to help you keep muscle while losing fat.

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Legion Forge is a fat burner that targets the stubborn fat around your belly and love handles. This product is specifically designed to accelerate fat loss while exercising in a fasted state. Legion Forge will maximize the fat burn while preserving your muscle mass. In addition, Forge delivers an energy surge that will power you through your workouts. There is no caffeine in this product, so you don’t have to worry about any jittery response.

Legion Forge contains clinically dosed levels of scientific ingredients. These include Yohimbine to burn fat faster by blocking the activity of alpha receptors. Brain function is boosted by way of CDP-Choline which improves the functioning of the brain. It is naturally sweetened and flavored making it the second-best fat burner muscle builder on our list.

3. Body Fortress Super Advanced Whey

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
90.4
image of Body Fortress Super Advanced Whey
Amazon Link
Materials
90
Ease of Use
95
Features
87
Side Effects
90
Product Purity
90
best offer for today
Amazon Link
Pros:

60 grams of protein per serve

8 grams of BCAAs

100% whey protein

Cons:

Contains carbs

The Body Fortress Super Advanced Whey comes in a 2-pound jar. This whey protein powder is enhanced with great ingredients like creatine and amino acids. It will help you train harder and build your lean muscle fast. Body Fortress wants its products to be affordable so they boast the highest quality without being the highest price.

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Body Fortress Super Advanced Whey is a super protein supplement that delivers a whopping 60 grams of protein to allow you to build lean mass. Upping your protein is a smart move when you want to lose fat and this fat-free supplement will allow you to burn fat while building muscle. Each serving contains 8 grams of branch chain amino acids, to fast track essential amino acids to your training muscles.

Body Fortress Super Advanced Whey uses 100% whey protein powder to deliver the protein to your working muscles in the fastest way possible. This product is manufactured in the USA in a GMP authorized facility. It mixes easily in water or milk and comes in a tasty chocolate flavor.

4. El Diablo Energy Gold

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
88.8
image of El Diablo Energy Gold
Amazon Link
Materials
90
Ease of Use
90
Features
87
Side Effects
90
Product Purity
87
best offer for today
Amazon Link
Pros:

Jitter-free stimulant effect

Antioxidants

Glutamine

Cons:

No caffeine

The El Diablo Energy Gold is designed to supercharge your metabolism for the best thermogenic activity and fat burning. Your waist will get smaller. It is also an all-natural mood enhancer. It is fortified with B vitamins, amino acids, and powerful antioxidants.

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El Diablo Energy Gold is a premium energy and cognitive enhancement fat loss product. It delivers a powerful surge to your metabolism and will stimulate your energy levels without the unnatural jittery effects that you get with other products. This product is packed with antioxidants, as well as B vitamins and cognitive supporting amino acids. All of the ingredients are clinically dosed and scientifically supported to boost fat burn while maintaining muscle mass.

El Diablo Energy Gold’s ingredient profile includes an extract from green tea and black tea, t l-glutamine, raspberry ketones, extract from cinnamon bark and bitter orange, caffeine anhydrous, conjugated linoleic acid (CLA), l-arginine, l-tyrosine, and 5-HTP. The product is manufactured in a Fortune 500 lab within the United States and comes with a money-back guarantee.

5. Old School Labs Vintage Burn

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
87.2
image of Old School Labs Vintage Burn
Amazon Link
Materials
85
Ease of Use
90
Features
86
Side Effects
90
Product Purity
85
best offer for today
Amazon Link
$49.99
Pros:

Great energy boost

Mental focus enhanced

Preserves muscle

Cons:

Does not suppress appetite

Old School Labs Vintage Burn is a great muscle preserving fat burner. It works for men or women with its thermogenic weight loss formula. The fat will fall away while muscle sticks around. It also helps your mental focus, improves your mood, and your energy. This supplement for muscle gain and weight loss is made with premium ingredients like green tea extract, raspberry ketones, and garcinia cambogia which will help you burn belly fat.

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Old School Labs Vintage Burn is a muscle preserving fat burner designed for both men and women. It contains a unique blend of scientifically proven ingredients that are designed to boost fat loss while preserving muscle tissue. It will also enhance mental focus and provide you with a huge energy surge for your workouts. The natural and safe ingredients contained in Vintage Burn have been hand-selected for their purity and potency.

Old School Labs Vintage Burn has been specially formulated to spare muscle and strength while burning fat. This product also contains a special blend designed to enhance your cognitive ability, so that you can focus like a laser on the workouts that will get you super shredded.

6. MuscleTech Nitro Tech Whey Protein

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
86.2
image of MuscleTech Nitro Tech Whey Protein
Amazon Link
Materials
85
Ease of Use
85
Features
86
Side Effects
90
Product Purity
85
best offer for today
Amazon Link
$32.99
Pros:

30 grams of protein per serving

Features L-carnitine, green tea & CLA

Clean and tastes great

Cons:

Some people did not like the taste

MuscleTech has created Nitro-Tech to give you an ultra-pure protein and help you manage your weight. Every scoop has C. canephora robusta which is a premium weight loss ingredient. It gives you a blend of whey peptides isolate to give you levels of essential BCAAs.

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This powder is designed exclusively to help you get ripped. It has 30 grams of protein with whey protein, peptides and protein isolate. All of these will help you build lean muscle. It is caffeine-free and instead contains C. canephora robusta which helps with weight loss.

It also features L-carnitine, CLA, and green tea extract. It has rosehip extract and kelp. This supplement is clean and tastes great without adding much of extra sugars and carbs.

7. NatureWise CLA 1250

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
85.6
image of NatureWise CLA 1250
Amazon Link
Materials
85
Ease of Use
84
Features
85
Side Effects
90
Product Purity
84
best offer for today
Amazon Link
$21.99
Pros:

Pure non-GMO CLA

Works for men or women

Supports weight loss and muscle gain

Cons:

Caused stomach issues for some

NatureWise CLA 1250 is ready to help you maximize your exercise with this weight loss supplement. The CLA comes from quality safflower oil and is 80% potent. This formula is plant-based and does not provide stimulation. It contains no addictive or artificial ingredients.

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The NatureWise supplement will help you build up your muscle to fat ratio. It works for men or women. The CLA pills work as thermogenic fat burners that get rid of fat storage and getting your body to burn fatty acids for energy.

This CLA comes from pure, non-GMO safflower oil which comes from certified sources. Unlike other weight loss supplements, these are made of simple, clean, natural ingredients. It is non-addictive, non-stimulating and safe.

8. Real Muscle Builder

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.8
image of Real Muscle Builder
Amazon Link
Materials
80
Ease of Use
82
Features
85
Side Effects
90
Product Purity
82
best offer for today
Amazon Link
Pros:

Super potent & bioavailable ecdysterone

Premium nitric oxide (N.O.) enhancement

7 products in 1

Cons:

May cause stomach issues

The Real Muscle Builder is perfect for lean, hard gains. It will increase your circulating nitric oxide levels and pump your muscles by improving oxygen and nutrient uptake. It is an all in one bodybuilding formula with no proprietary blends.

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The Real Muscle Builder has potent and bioavailable ecdysterone for protein synthesis. It has R-Lipoic Acid Sodium helps along the food to fuel process. This is the premium muscle building formula which will help with those lean gains. It will help you increase strength and harden up.

This supplement for weight loss and muscle gain contains quality nitric oxide enhancement as well as arginase inhibitors to help keep you pumped all day by maximizing muscle growth and blood flow. You would spend a lot of money if you tried to purchase all of these ingredients individually but with Real Muscle, it is like having seven in one. You have your stack in a single bottle.

9. MusclePharm Combat Protein Powder

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.4
image of MusclePharm Combat Protein Powder
Amazon Link
Materials
80
Ease of Use
82
Features
85
Side Effects
90
Product Purity
80
best offer for today
Amazon Link
$64.99
Pros:

Mixes easily

Tested for banned ingredients

Protein from 5 sources

Cons:

Can cause some digestive issues

MusclePharm Combat Protein Powder helps you grow lean muscle. It has a variety of protein blends that all digest at different rates which helps to feed your muscles for longer. This formula has won awards and helps you create an environment building muscles which will last longer.

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The MusclePharm Combat Protein Powder was created for serious athletes who demand the very best for building muscle growth and strength. This whey protein powder mixes perfectly with milk, water, fruits, and vegetables. You can use it to make fantastic shakes and smoothies.

The powder contains 25 grams of protein which comes from five different sources. Some of these digest quickly while others digest more slowly. It will deliver performance and fuel your muscles for hours. This formula is certified as a banned substance tested. It has undergone rigorous checks and testing to make sure it is not contaminated.

10. Genius Fat Burner

The rating is based on the average rating (1-100) from all the criteria in which we rated this product.
83.2
image of Genius Fat Burner
Amazon Link
Materials
80
Ease of Use
81
Features
85
Side Effects
90
Product Purity
80
best offer for today
Amazon Link
$49.99
Pros:

9 clinically backed ingredients

Helps to boost memory and clarity

It is non-habit forming

Cons:

May cause stomach issues

The Genius Fat Burner is for users who do not want their intelligence insulted for falling for scam supplements. It is not built around caffeine and cheap stimulants. Instead, they use clinically proven cognitive enhancers and clinically studied weight loss and fat burning ingredients.
This supplement has an all-star lineup of nine trademarked ingredients. They are all tested to be tried, true and potent.

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This is a true premium fat burner muscle gainer supplement that is different than anything else on the market. It has nine clinically backed ingredients that support brain health and fat loss. The ingredients are tested by a third party for safety.

The formula is made for a natural form of fat loss and every ingredient is supported by clinical trials. They are made without proprietary blends. It will also help you boost memory, clarity and focus without any artificial stimulants. Cognizin, AlphaSize & TeaCrine help with your key brain functions like concentration and focus. It speeds up your metabolic rate and thermogenesis as well as reducing stress, controlling appetite and helping improve your mood.

Criteria Used for Evaluation

Materials

A few different ingredients are the most effective at building muscle strength and helping with fat loss. The best supplements for weight loss and muscle gain we have chosen reflect the highest quality in them.

The biggest ingredient is going to be protein. It is nice to have some which and slow release and some fast release so they feed your muscles for an extended period of time. Whey protein is quality. HMB will also help to maintain muscle mass.

Creatine monohydrate is a top ingredient for exercise performance. It is very safe to consume, even in high doses. It increases the water content in cells so it can increase muscle mass, but may cause some weight gain.

BCAAs are also important. They increase muscle growth by stimulating the process of making muscles. This works even better if there is whey protein included.

Nitric oxide is important because it is one of the most important molecules for blood vessel health. It helps with preventing muscle soreness. It also helps to keep your blood pressure lower. Citrulline helps increase your nitric oxide.

Taurine is also clinically proven to boost your performance in the gym. It is safe with no known side effects. It helps your body maintain cellular hydration. It also helps muscles work harder and with less fatigue during your workout.

L-glutamine is another important ingredient in muscle strengthening supplements. It is a protein building block and helps with muscle gain. It helps to improve muscle mass and strength. It also helps with muscle soreness. It also helps you speed up muscle recovery after an intense workout.

Ingredients like yohimbine, green tea extract, and garcinia cambogia are believed to help with the fat loss so it is good to see them included as well.

All of these ingredients are helpful in optimizing your muscle strength so you want the best supplements for muscle gain and strength which contains as many as possible. Of course, the purer the ingredients the better. Look for a supplement that has been tested by a third party or even have a guarantee as to their effectiveness.

Ease of Use

If the best supplements for muscle gain and fat loss are going to become part of your routine, it needs to be easy to use and it needs to match with your workout style. If you mostly work out at a gym, you need a form that is easy to take with you or something you can take before you leave. The container needs to be simple as well. You want a bottle with a secure lid or a resealable bag.

Some of the supplements come in powder form. If this is the type you choose, you want to make sure it is something that mixes easily without being clumpy. You should also be able to mix it with something you have readily at hand.

If you are at the gym, having something which only mixes with milk is going to be a little inconvenient. Having a powder that mixes easily with water is probably the most convenient or being able to mix it with something you enjoy drinking.

A lot of these supplements come in capsule form. Hopefully, you will find one which is not too huge and easy to take. Some people like to break the capsules open and mix them with a drink, but the ingredients are known to be bitter so if you do that make sure you mix it with a drink which has a strong flavor.

Features

Features are important in a quality supplement so it is wise to do your research. Check out the ingredients to make sure they are pure and that it contains the supplements you need to work towards your goals. It should be guaranteed to build muscle and help with fat loss. It should also give you strength and energy and help with recovery after your workout.

What type of container does the supplement come in? If you want something you can take to the gym with you, you will not want one which ones in a big tub. You will want a bottle of capsules or even a resealable bag.

Make sure the ingredients are all-natural and not full of preservatives or artificial colors and flavors. Check whether it comes in a powder, capsule, or caplet. If you have digestive issues, find a supplement that will be easy on your stomach.

Having the ingredients micronized is a nice feature too. The particles are broken down even smaller which makes them easier to swallow and also makes them more soluble. This also makes it easier to digest.

We searched the current market to find the products we felt had the most convenient and useful features, especially to help you build muscle strength before and after your workout.

Side Effects

There are ingredients in the best supplements for weight loss and muscle gain which can cause side effects so you will want to be aware if you have some of these symptoms, and especially keep an eye out for any allergic reactions.

If the supplement contains creatine, be aware of stomach pain or cramping, diarrhea, nausea or weight gain because of your muscles retaining water.

If it contains glutamine, pay special attention because it may be dangerous for people with conditions like cirrhosis, seizures, mania or other conditions. The most common side effects are coughing or hoarseness and issues with bathroom habits.

If the supplement contains nitric oxide, you will want to watch for abdominal pain, diarrhea, bloating, gout, worsening asthma, or low blood pressure.

This is not to say these side effects are common or will happen to you. Probably the best advice we could recommend would be to watch for allergy symptoms and to always consult your health care professional before you starting taking a new supplement. Always pay attention to your doctor and your body.

Product Purity

When researching the best supplements for muscle gain and strength, you want to find the ones which have the purest forms of each ingredient. You will see by the top choices on our list that this is an important aspect. You work out to keep your body in optimal shape, so you want to make sure that what you put in it is optimal as well.

There are third parties that will test supplements for impurities. Be sure to read the label carefully. If you have any questions about whether an ingredient is safe or good for your particular health, contact the manufacturer or consult with your health care professional.

Look for a supplement that has all-natural ingredients. You do not want something which is packed with artificial colors or flavors, even if that makes it taste better. You also want something without preservatives in it.

The U.S. Food and Drug Administration does not analyze the contents of best supplements for muscle gain and strength but they do give out Good Manufacturing Practices (GMP) which are a set of expectations and requirements by which they must be manufactured and stored to keep quality.

The people who manufacture supplements guarantee the purity, strength, and composition of their products.

One other consideration is making sure your supplement does not contain any minor ingredients which you may be allergic to. Check the label for soy, dairy, yeast, sugar, or starch. Some are even guaranteed to work with a vegan diet.

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expert tips icon
Get plenty of protein

When you are working on gaining lean muscle and losing fat it is critical you get enough protein. Having a supplement with fast release and slow release together is handy so it feeds your muscles long. Just make sure you are consuming more protein than what your body is breaking down naturally.

Some athletes have a hard time getting all the protein they need to build muscle so supplements help. The most popular are casein, whey, or soy.
If you are athletic and trying to gain muscle, you should eat about 0.5-0.9 grams of protein per pound.

They work with your lifestyle

In order for these supplements to work in helping you gain muscle and lose fat, you need to incorporate a healthy exercise program into your routine as well as good nutritional habits. In order to gain muscle mass, you need to consume enough calories as well as get plenty of exercises, preferably with weights. Once those are in check, you are ready to include supplements.

Other Factors to Consider

Portability

If you workout at home or have your own home gym, then portability is not much of a consideration but if you have a gym membership or even go elsewhere in the building, it is nice to have a supplement you can take with you especially if it is to be taken after your workout. You might want to consider a pill, caplet or something you can pour into your water bottle.

Frequently Asked Questions

q: Does a fat burner reduce muscle size?

a:

A fat burner is not going to help you unless you are already on a deficit. Diet and workout are mostly responsible for fat loss with a supplement being a small percentage of help.

q: Can fat be converted into muscle?

a:

Your body cannot turn fat into muscle and in the reverse muscle cannot turn into fat either. If your body lacks protein, it will burn stored fat and also muscle. Then your muscle cells shrink.

q: Is apple cider vinegar a fat burner?

a:

According to a study, adding a couple of tablespoons of apple cider vinegar into your diet it can help you lose weight. It will also help lower your fat percentage, lose belly fat and decrease blood triglycerides.

q: Which foods help burn belly fat?

a:

There are quite a few but a few favorites like avocados, bananas, yogurt, berries, chocolate skim milk, green tea, citrus, or whole grains work well.

q: What are the benefits of gaining muscle mass?

a:

Not only will you look great, but gaining muscle mass will benefit you by increasing your strength and metabolism. It also helps your resistance to injury. Muscles help your body turn food into fuel and reduce your risk of diabetes.

Sources